Wednesday, June 28, 2017

Study finds more childhood cancer survivors would likely benefit from genetic screening

April 3, 2017 -- "Twelve percent of childhood cancer survivors carry germline mutations that put them or their children at increased risk of developing cancer, according to a landmark study presented today at the annual meeting of the American Association for Cancer Research. The findings from St. Jude Children's Research Hospital are expected to have an immediate and potentially life-saving impact on the growing population of childhood cancer survivors. ..."

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Early deaths from childhood cancer up to 4 times more common than previously reported

March 8, 2017 -- "... A study published in the Journal of Clinical Oncology explores this challenging population, finding that death within a month of diagnosis is more likely in very young children and those from minority racial and ethnic groups even independent of low socioeconomic status. ..."

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Genetic Clues Help Prevent Late Effects

"... Dr Smita's group and others are systematically studying the genome in order to identify genetic predisposition markers for some of the late effects that are encountered, in turn identifying children at higher risk and also those at lower risk despite the same exposure. ..."

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A new urgency to protect survivors of childhood cancer

A great Washington Post story from this past December on the negative late effects from the successful treatment of childhood cancers:

"... One of medicine’s greatest successes is the sharp rise in survival rates for children with cancer. But the flip side of that success is that many of those children are turning up years or even decades later with serious and sometimes life-threatening complications, including second cancers, heart disorders, cognitive problems and infertility. ..."

A specific example that hits close to home, "... By age 50, 1 in 3 women who received chest radiation for Hodgkin’s lymphoma will develop breast cancer, compared with less than 1 in 20 in the general population, Armstrong said. ..."

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Letter to the Editor: Childhood cancer bill

"... As a pediatric oncology nurse, I have seen too many young adults who survived cancer in childhood fall through the cracks as they transition to adult care. It is essential that we help support these survivors as they face the effects of treatment later in life. ..."

Read the letter from May 29, 2017 at

Study Finds a Decline in Late Effects After Childhood Treatment

"... Rather than being evenly distributed across cancer types, however, these gains were seen only in patients treated for certain cancers. ..."

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